St Louis Small Business Resources
Starting and running a small business requires resources. There are businesses, government groups, and nonprofits ready to help you.
We’ve compiled a list of St. Louis small business resources and created tools and guides to help you operate a successful business in Missouri.
Starting a business? Get access to small business resources and support when you start an LLC with Northwest ($29 + State Fees).

Local Resources for Small Business in St. Louis
Using local resources can make a big difference. Here are some of the best local resources for small businesses in St. Louis.
To get more Missouri business resources, visit our Missouri Small Business Resources guide.
Center for Emerging Technologies
Overview
CET is the largest and oldest Innovation Center in Missouri, boasting a variety of programs that support startups in the field of information technology, bioscience, and manufactured products. Their highlights include Square One Ignite training, Bootcamp training program, and other workshops and seminars. They also host the House of Genius St Louis collaborative program and the weekly Venture Cafe Meeting. Most of their programs are available for early-stage entrepreneurs at little or no cost. Their physical space is called CIC@CET.
Restrictions
Training programs focus on the field of information technology, bioscience, and manufactured products.
Contact Information
Office Address:
20 South Sarah St.
St Louis, MO 63108
Phone Number: 314-615-6900
Email: gramirezarellano@cortexstl.org
Social Media:
TRUiC Business Resources
CIC St. Louis
Overview
CIC St. Louis is a coworking space that offers startups of any size a fluid workspace, along with connections to a diverse network in the community. The highlight of this space includes a wet lab that is ideal for chemical or biological experiments. Lab spaces range from 500 to 2,000 sqft that can accommodate teams of 2 to 10. In addition to life science and biomedical support, they also support any innovation in the field of public relations, law and education.
Contact Information
Office Address:
4240 Duncan Ave.
Suite 200
St. Louis, MO 63110
Phone Number: 314-615-6301
Email: space-stl@cic.us
Social Media:
The Hive 44
Overview
HIVE 44 is a coworking/meeting/event space that offers several membership plans ranging from mail/package services to private offices. They also rent out event/meeting, and conference space, with catering available upon request.
Contact Information
Office Address:
1710-1730 Fenpark Dr.
Fenton, MO 63026
Phone Number: 636-405-3130
Email: info@thehive44.com
Social Media:
Missouri SBDC in St. Louis Region
Overview
The greatest strength of the SBDC is their free, confidential, 1-on-1 business mentoring for anyone who seeks it. Sometimes in order to be considered for mentoring from one of their professional business advisors, you may have to attend a class/workshop or at least present your business plan. SBDC's are located all throughout the state and you should use the SBDC closest to your location if possible, but you can often transfer to a different location if they do not fit your needs.
Social Media:
SCORE St. Louis
Overview
SCORE (Service Corp of Retired Executives) is a leading, nation-wide organization that has assisted millions of entrepreneurs over its 50+ years of operation. SCORE is a resource partner of the SBA that offers access to a network of experienced business leaders who donate time to mentor entrepreneurs and small business owners. They also host free or inexpensive workshops online and at 300 local chapters around the United States. Mentoring can be conducted either in person or remotely and is always free and confidential, no matter how often you take advantage of this service.
T-REX
Overview
T-Rex is a tech incubator and coworking space located in St. Louis. They have several in-house organizations for entrepreneurial support on funding and mentorship, as well as occasional entrepreneur-related events. Non-members can book their spaces for events, as long as the theme of the event aligns with the mission of T-Rex as a non-profit tech incubator. This place is ideal for any tech startup entrepreneur.
Contact Information
Office Address:
911 Washington Ave.
St Louis, MO 63101
Phone Number: 314-241-7500
Email: kathleen@downtowntrex.com
Social Media: